Hippocampal protocol a powerful new tool for research, treatment

From Friends of the Semel Institute: After six years of painstaking research, a UCLA team has helped create a new “gold standard” method for recognizing signs of Alzheimer’s disease in the brain. Led by by Dr. Liana Apostolova, director of the neuroimaging laboratory at the Mary S. Easton Center for Alzheimer’s Disease Research, the researchers confirmed the effectiveness of MRI measurements of atrophy in the hippocampus to track the pathologic changes that are hallmarks of the disease — the progressive development of amyloid plaques and neurofibrillary tangles in the brain. “This hippocampal protocol … will serve as a powerful tool in clinical trials for measuring the efficacy of new drugs in slowing or halting disease progression,” said Apostolova. Learn more in this UCLA Newsroom story.

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