FDA Approves First Drug for Binge-Eating Disorder

????????????????????????????????????????????????From Psychiatric News Alert: Vyvanse—a medication approved in 2007 for attention-deficit/hyperactivity disorder (ADHD)—is the first medication to be approved by the U.S. Food and Drug Administration (FDA) intended to treat binge-eating disorder.

“Binge eating can cause serious health problems and difficulties with work, home, and social life,” said FDA Division of Psychiatry Products Director Mitchell Mathis, M.D. “The approval of Vyvanse provides physicians and patients with an effective option to help curb episodes of binge eating.” The drug was reviewed under the FDA’s priority review program, which expedites the review process of drugs that are intended to treated serious conditions for which there are limited therapy options available.

The FDA approved Vyvanse based on data generated from two clinical trials with 724 adults with moderate-to-severe binge-eating disorder. The results showed that participants taking Vyvanse experienced a decrease in the number of binge-eating days per week and had fewer obsessive-compulsive binge-eating behaviors compared with those taking placebo. Most serious side effects reported by individuals taking Vyvanse included dry mouth, insomnia, increased heart rate, and anxiety.

Vyvanse’s Medication Guide notes the risks associated with the medication’s use, such as increased risk of psychotic or manic symptoms, even in individuals without a prior history of psychotic illness. The FDA emphasized that Vyvanse is not approved for, or recommended for, weight loss.

Vyvanse is marketed by Shire U.S. Inc.

View the FDA press announcement on Vyvanse. To read more about eating disorders and pharmacotherapies used to treat eating disorders, see the Psychiatric News article “Expert Hopeful About Future of Treatment for Eating Disorders.”

Image credit: Monkey Business | DPC

Caution: Parent Talking Weight with Child May Increase Risk of Eating Disorder

Study Suggests Talking About “Eating Healthy Foods” is Safer.

From Psychiatric News Alert (8/5/13): When parents discuss weight issues with their adolescents, it may encourage them to develop eating disorders, a large community-based study reported in JAMA Pediatrics suggests. The study found, for example, that youngsters were more likely to engage in unhealthy eating behaviors such as extreme dieting, laxative use, and binge eating when their parents talked about weight than when they talked about eating healthy foods. This was the case for overweight youth as well as for those who were not overweight. In addition, binge eating was found to be more prevalent among adolescents whose mothers discussed weight than among adolescents whose mothers didn’t.

“I think these are important findings,” Michael Devlin, M.D., co-director of eating disorders research at the New York State Psychiatric Institute, told Psychiatric News. “They support the idea that, despite our concerns about obesity and its comorbidities, the most useful health promotion messages relate to lifestyle and not weight, and that weight-related messaging, particularly messages that evoke shame or contribute to stigma, can be counterproductive.”

Body dissatisfaction is another major factor that has been linked with the development of eating disorders in young people. Read more about that issue in Psychiatric News here, and read about research on binge-eating disorder here.