Two Continuation Treatments Found Effective for Depression

From Psychiatric News Alert: Continuing treatment of patients with major depressive disorder following acute-phase cognitive therapy works equally well regardless of whether patients are given fluoxetine or additional cognitive therapy, according to a study released today inJAMA Psychiatry.

The researchers randomized 241 adult responders out of a total of 523 who began treatment—86 to receive another eight months of cognitive therapy, 86 to receive fluoxetine, and 69 to receive a placebo.

Relapse or recurrence rates were almost the same for the continued cognitive-therapy and fluoxetine groups during the eight months of treatment, said the researchers. However, the cognitive-therapy patients were more likely to accept randomization, stay in treatment longer, and attend more treatment sessions than those in the other two cohorts.

While both forms of treatment demonstrated benefit over the course of the trial, the researchers cautioned that some patients may need further help. “After active therapies were discontinued, the preventive effects of both treatments dissipated, suggesting that some higher-risk patients may benefit from additional continuation/maintenance therapies,” concluded Robin Jarrett, Ph.D., of the University of Texas Southwestern Medical Center, Dallas, and colleagues.

For more information in Psychiatric News about treatments for depression, see “Brain-Area Activity Might Predict Depression Treatment Response.”

(Image: Wavebreak Media/Shutterstock/com)

What is Cognitive Behavioral Therapy?

Cognitive Behavioral Therapy (CBT) is a blend of two therapies: cognitive therapy (CT) and behavioral therapy. CT was developed by psychotherapist Aaron Beck, M.D. in the 1960’s. CT focuses on a person’s thoughts and beliefs, and how they influence a person’s mood and actions, and aims to change a person’s thinking to be more adaptive and healthy. Behavioral therapy focused on a person’s actions and aims to change unhealthy behavior patterns.

CBT helps a person focus on his or her current problems and how to solve them. Both patient and therapist need to be actively involved in this process. The therapist helps the patient learn how to identify distorted or unhelpful thinking patterns recognize and change inaccurate beliefs, related to others in more positive ways, and change behaviors accordingly.

CBT can be applied and adapted to many conditions, including depression, bipolar disorder, Anxiety disorders, eating disorders, schizophrenia and schizoaffective disorder. For instance, people with bipolar disorder usually need to take medication, such as a mood stabilizer. But CBT is often used as an added treatment. The medication can help stabilize a person’s mood so that he or she is receptive to psychotherapy and can get the most out of it. CBT can help a person cope with bipolar symptoms and learn to recognize when a mood shift is about to occur. CBT also helps a person with bipolar disorder stick with a treatment plan to reduce the chances of relapse (e.g., when symptoms return).

With schizophrenia, the disorder generally requires medication first. But research has shown that CBT, as an add-on to medication, can help a patient cope with schizophrenia, helping patients learn more adaptive and realistic interpretations of events. Patients are also taught various coping techniques for dealing with “voices” or other hallucinations. They learn how to identify what triggers episodes of the illness, which can prevent or reduce the chances of relapse. CBT for schizophrenia also stresses skill-oriented therapies. Patients learn skills to cope with life’s challenges. The therapist teaches social, daily functioning, and problem-solving skills. This can help patients with schizophrenia minimize the types of stress that can lead to outbursts and hospitalizations.

CBT for schizoaffective treatment shares elements of each of the foregoing. Over the past two decades, CBT for schizophrenia and schizoaffective disorder has received considerable attention in the United Kingdom and elsewhere abroad. While this treatment continues to develop in the United States, the results from studies in the United Kingdom and other countries have encouraged therapists in the U.S. to incorporate this treatment into their own practices. In this treatment, often referred to as cognitive behavioral therapy for psychosis (CBT-P).

For more information, see the National Institute for Mental Health Site and NAMI.

From: National Institute of Mental Health and NAMI National.